cDNA clone of hepatitis A virus encoding a virulent virus: induction of viral hepatitis by direct nucleic acid transfection of marmosets.

Direct inoculation of marmoset livers with an in vitro transcription mixture containing cDNA and full-length genomic RNA transcripts of hepatitis A virus resulted in acute viral hepatitis. Elevations in serum levels of liver enzymes were correlated with appearance of antibody to hepatitis A virus. G...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Emerson, S U, Lewis, M, Govindarajan, S, Shapiro, M, Moskal, T, Purcell, R H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC240161/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1328684/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.11.6649-6654.1992
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