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The E5 gene product of rhesus papillomavirus is an activator of endogenous Ras and phosphatidylinositol-3′-kinase in NIH 3T3 cells

We examined the effect of two rhesus papillomavirus 1 (RhPV) oncogenes on cytokine-induced signal transduction pathways leading to the possible activation of Ras protein (p21(ras)) and phosphatidylinositol kinase. p21(ras) in both the activated (GTP-bound) and inactivated (GDP-bound) states were qua...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ghai, Jyotsna, Ostrow, Ronald S., Tolar, Jakub, McGlennen, Ronald C., Lemke, Todd D., Tobolt, Diane, Liu, Zhanjiang, Faras, Anthony J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24014/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8917513/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.23.12879
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