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A curved RNA helix incorporating an internal loop with G·A and A·A non-Watson–Crick base pairing

The crystal structure of the RNA dodecamer 5′-GGCC(GAAA)GGCC-3′ has been determined from x-ray diffraction data to 2.3-Å resolution. In the crystal, these oligomers form double helices around twofold symmetry axes. Four consecutive non-Watson–Crick base pairs make up an internal loop in the middle o...

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Autori principali: Baeyens, Katrien J., De Bondt, Hendrik L., Pardi, Arthur, Holbrook, Stephen R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences of the USA 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC24009/
https://ncbi.nlm.nih.gov/pubmed/8917508
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