Molecular basis of viral persistence: a single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with suppression of the antiviral cytotoxic T-lymphocyte response and establishment of persistence.

Isolates of lymphocytic choriomeningitis virus (LCMV) that elicit a cytotoxic T-lymphocyte response (CTL+) have been compared with isolates that suppress the CTL response (CTL-) in an effort to map this phenotype. A single amino acid change in the glycoprotein of the LCMV Armstrong (ARM) strain is c...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Salvato, M, Borrow, P, Shimomaye, E, Oldstone, M B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239996/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1840619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.4.1863-1869.1991
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