Autonomous parvovirus DNA replication requires topoisomerase I and its activity is increased during infection.

Topoisomerases I and II (topo I and topo II) are nuclear enzymes functioning to resolve DNA topological problems during replication, transcription, and other DNA processes. We tested the effects of camptothecin and VP16, specific inhibitors of topo I and II, respectively, on the DNA replication of p...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Gu, M L, Rhode, S L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239959/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1847484/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.3.1662-1665.1991
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