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Determinants of persistence and demyelination of the DA strain of Theiler's virus are found only in the VP1 gene.

The DA strain of Theiler's virus persists in the central nervous systems of mice and causes chronic inflammation and demyelination. The GDVII strain, on the other hand, causes an acute encephalitis that kills the host in a matter of days. We constructed a series of recombinants between two infe...

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Publicado en:J Virol
Autores principales: Tangy, F, McAllister, A, Aubert, C, Brahic, M
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1991
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239948/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1844214/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.3.1616-1618.1991
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