Carboxy-terminally truncated dengue virus envelope glycoproteins expressed on the cell surface and secreted extracellularly exhibit increased immunogenicity in mice.

Recombinant vaccinia viruses expressing C-terminally truncated E's that ranged in length from 9 to 99% of the N-terminal sequence were constructed. The overall antigenicity of the E products was analyzed by radioimmunoprecipitation, using dengue virus hyperimmune mouse ascitic fluid (HMAF) or an ant...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Men, R H, Bray, M, Lai, C J
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1991
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239918/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1995950/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.3.1400-1407.1991
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