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A specific inhibitor of cysteine proteases impairs a Vif-dependent modification of human immunodeficiency virus type 1 Env protein.

The Vif protein of human immunodeficiency virus type 1 (HIV-1) regulates viral infectivity. Virions produced in cell culture after transfection by a Vif-negative molecular clone show a dramatic decrease in infectivity for susceptible CD4+ cell lines, although the Vif protein does not appear to be a...

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Détails bibliographiques
Auteurs principaux: Guy, B, Geist, M, Dott, K, Spehner, D, Kieny, M P, Lecocq, J P
Format: Artigo
Langue:Inglês
Publié: 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC239908/
https://ncbi.nlm.nih.gov/pubmed/1995946
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