Induction of human immunodeficiency virus type 1 expression in chronically infected cells is associated primarily with a shift in RNA splicing patterns.

We have analyzed the kinetics of human immunodeficiency virus type 1 (HIV-1) RNA induction in chronically infected T cells and promonocytes. A substantial amount of spliced mRNAs and assembled virions was found in resting cells. Induction increased the steady-state level of total HIV-1 RNA by 4-fold...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Michael, N L, Morrow, P, Mosca, J, Vahey, M, Burke, D S, Redfield, R R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1995944/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.3.1291-1303.1991
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