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Differential induction of structural changes in the simian virus 40 origin of replication by T antigen.

The ATP-dependent binding of the simian virus 40 (SV40) large tumor antigen (T antigen) to the SV40 origin of replication (ori) results in the structural distortion of two critical elements within flanking regions of ori and the untwisting of the DNA helix. We examined the effect of changes in tempe...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Borowiec, J A, Dean, F B, Hurwitz, J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239892/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1847451/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.3.1228-1235.1991
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