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Defining nucleic acid-binding properties of avian retrovirus integrase by deletion analysis.

Integration of retroviral DNA into the host genome requires the activity of retrovirus-encoded integration protein IN. We expressed Rous sarcoma virus (RSV) IN, 286 amino acid residues in length, by using in vitro transcription, followed by in vitro translation in rabbit reticulocyte lysate. The nuc...

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Published in:J Virol
Main Authors: Mumm, S R, Grandgenett, D P
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1991
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239882/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1847445/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.3.1160-1167.1991
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