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Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques

HIV infiltrates the CNS soon after an individual has become infected with the virus, and can cause dementia and encephalitis in late-stage disease. Here, a global metabolomics approach was used to find and identify metabolites differentially regulated in the cerebrospinal fluid (CSF) of rhesus macaq...

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Detalles Bibliográficos
Main Authors: Wikoff, William R., Pendyala, Gurudutt, Siuzdak, Gary, Fox, Howard S.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2398736/
https://ncbi.nlm.nih.gov/pubmed/18521184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34138
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