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Mapping the Functional Interaction of Sco1 and Cox2 in Cytochrome Oxidase Biogenesis

Sco1 is implicated in the copper metallation of the Cu(A) site in Cox2 of cytochrome oxidase. The structure of Sco1 in the metallated and apo-conformers revealed structural dynamics primarily in an exposed region designated loop 8. The structural dynamics of loop 8 in Sco1 suggests it may be an inte...

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Autores principales: Rigby, Kevin, Cobine, Paul A., Khalimonchuk, Oleh, Winge, Dennis R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397465/
https://ncbi.nlm.nih.gov/pubmed/18390903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710072200
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