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Glial Cell Aquaporin-4 Overexpression in Transgenic Mice Accelerates Cytotoxic Brain Swelling

Aquaporin-4 (AQP4) is a water transport protein expressed in glial cell plasma membranes, including glial cell foot processes lining the blood-brain barrier. AQP4 deletion in mice reduces cytotoxic brain edema produced by different pathologies. To determine whether AQP4 is rate-limiting for brain wa...

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書誌詳細
主要な著者: Yang, Baoxue, Zador, Zsolt, Verkman, A. S.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397463/
https://ncbi.nlm.nih.gov/pubmed/18375385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801425200
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