Label-Free, High-Throughput Measurements of Dynamic Changes in Cell Nuclei Using Angle-Resolved Low Coherence Interferometry

Accurate measurements of nuclear deformation, i.e., structural changes of the nucleus in response to environmental stimuli, are important for signal transduction studies. Traditionally, these measurements require labeling and imaging, and then nuclear measurement using image analysis. This approach...

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Detalhes bibliográficos
Main Authors: Chalut, Kevin J., Chen, Sulin, Finan, John D., Giacomelli, Michael G., Guilak, Farshid, Leong, Kam W., Wax, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Spectroscopy, Imaging, Other Techniques
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397353/
https://ncbi.nlm.nih.gov/pubmed/18326642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.124107
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