Analysis of Self-Associating Proteins by Singular Value Decomposition of Solution Scattering Data

We describe a method by which a single experiment can reveal both association model (pathway and constants) and low-resolution structures of a self-associating system. Small-angle scattering data are collected from solutions at a range of concentrations. These scattering data curves are mass-weighte...

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Main Authors: Williamson, Tim E., Craig, Bruce A., Kondrashkina, Elena, Bailey-Kellogg, Chris, Friedman, Alan M.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2008
Teme:
Spectroscopy, Imaging, Other Techniques
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397332/
https://ncbi.nlm.nih.gov/pubmed/18212017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.113167
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