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Long-term exposure to high corticosterone levels attenuates serotonin responses in rat hippocampal CA1 neurons

Recent studies indicated that hyperactivity of the hypothalamo-pituitary-adrenal system is a considerable risk factor for the precipitation of affective disorders, most notably of major depression. The mechanism by which this hyperactivity eventually leads to clinical symptoms of depression is unkno...

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Detalhes bibliográficos
Main Authors: Karten, Y. J. G., Nair, S. M., van Essen, L., Sibug, R., Joëls, M.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23969/
https://ncbi.nlm.nih.gov/pubmed/10557342
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