A Quantitative MR Imaging Assessment of Leukoencephalopathy in Children Treated for Acute Lymphoblastic Leukemia without Irradiation

PURPOSE: Intravenous methotrexate (IV-MTX), an effective treatment for acute lymphoblastic leukemia (ALL), has a significant toxic effect on the central nervous system, with leukoencephalopathy (LE) being the most common form. The purpose of this study was to use objective quantitative MR imaging to...

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Main Authors: Reddick, Wilburn E., Glass, John O., Helton, Kathleen J., Langston, James W., Li, Chin-Shang, Pui, Ching-Hon
Format: Artigo
Jezik:Inglês
Izdano: American Society of Neuroradiology 2005
Teme:
Pediatrics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396879/
https://ncbi.nlm.nih.gov/pubmed/16219848
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