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P2X7 receptors on osteoblasts couple to production of lysophosphatidic acid: a signaling axis promoting osteogenesis
Nucleotides are released from cells in response to mechanical stimuli and signal in an autocrine/paracrine manner through cell surface P2 receptors. P2rx7(−/−) mice exhibit diminished appositional growth of long bones and impaired responses to mechanical loading. We find that calvarial sutures are w...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396816/ https://ncbi.nlm.nih.gov/pubmed/18519738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708037 |
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