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Molecular determinants of the modulation of cyclic nucleotide-activated channels by calmodulin

The action of calmodulin (CaM) on target proteins is important for a variety of cellular functions. We demonstrate here, however, that the presence of a CaM-binding site on a protein does not necessarily imply a functional effect. The α-subunit of the cGMP-gated cation channel of human retinal cones...

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Detalhes bibliográficos
Main Authors: Grunwald, Maria E., Zhong, Haining, Lai, Jun, Yau, King-Wai
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23967/
https://ncbi.nlm.nih.gov/pubmed/10557340
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