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Hyper innate responses in neonates lead to increased morbidity and mortality after infection

Neonates suffer high morbidity and mortality in infection, presumably because of the lack of a fully developed adaptive and innate immune system. Evidence of poor innate responses in neonates has been shown by using a model that sensitizes the host to Toll-like receptor (TLR)-mediated inflammation w...

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Main Authors: Zhao, Jie, Kim, Kwang Dong, Yang, Xuanming, Auh, Sogyong, Fu, Yang-Xin, Tang, Hong
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396698/
https://ncbi.nlm.nih.gov/pubmed/18490660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800152105
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