Proinflammatory role of amphiregulin, an epidermal growth factor family member whose expression is augmented in rheumatoid arthritis patients

BACKGROUND: The epidermal growth factor (EGF) and EGF receptor (EGFR) families play important roles in the hyperplastic growth of several tissues as well as tumor growth. Since synovial hyperplasia in rheumatoid arthritis (RA) resembles a tumor, involvement of the EGF/EGFR families in RA pathology h...

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Detalhes bibliográficos
Main Authors: Yamane, Shoji, Ishida, Satoru, Hanamoto, Yukie, Kumagai, Ken-ichi, Masuda, Riako, Tanaka, Konagi, Shiobara, Noriyuki, Yamane, Noriko, Mori, Toshihito, Juji, Takuo, Fukui, Naoshi, Itoh, Tsunetoshi, Ochi, Takahiro, Suzuki, Ryuji
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396620/
https://ncbi.nlm.nih.gov/pubmed/18439312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-5-5
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