Automated Nuclear Analysis of Leishmania major Telomeric Clusters Reveals Changes in Their Organization during the Parasite's Life Cycle

Parasite virulence genes are usually associated with telomeres. The clustering of the telomeres, together with their particular spatial distribution in the nucleus of human parasites such as Plasmodium falciparum and Trypanosoma brucei, has been suggested to play a role in facilitating ectopic recom...

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Bibliographic Details
Main Authors: Dossin, Fernando de M., Dufour, Alexandre, Dusch, Elodie, Siqueira-Neto, Jair L., Moraes, Carolina B., Yang, Gyong Seon, Cano, Maria Isabel, Genovesio, Auguste, Freitas-Junior, Lucio H.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396463/
https://ncbi.nlm.nih.gov/pubmed/18545650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002313
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