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Protein SUMOylation is massively increased in hibernation torpor and is critical for the cytoprotection provided by ischemic preconditioning and hypothermia in SHSY5Y cells

Hibernation torpor provides an excellent natural model of tolerance to profound reductions in blood flow to the brain and other organs. Here, we report that during torpor of 13-lined ground squirrels, massive SUMOylation occurs in the brain, liver, and kidney. The level of small ubiquitin-related mo...

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Bibliografiske detaljer
Main Authors: Lee, Yang-ja, Miyake, Shin-ichi, Wakita, Hideaki, McMullen, David C, Azuma, Yoshiaki, Auh, Sungyoung, Hallenbeck, John M
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396349/
https://ncbi.nlm.nih.gov/pubmed/16955077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jcbfm.9600395
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