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A major role for Mcl-1 antiapoptotic protein in the IL-6-induced survival of human myeloma cells
Interleukin-6 (IL-6) is a major survival factor for malignant plasma cells involved in multiple myeloma. Using an RNase protection assay, we looked for gene expression of 10 anti- and pro-apoptotic Bcl-2-family proteins in 12 IL-6-dependent human myeloma cell lines (HMCL). A high Mcl-1 gene expressi...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396235/ https://ncbi.nlm.nih.gov/pubmed/12771946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1206423 |
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