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Development of new derivatives of primaquine by association with lysosomotropic carriers

On the basis of the drug-carrier concept of chemotherapy, we entrapped primaquine in liposomes, and linked it to an amino acid (leucine), and to peptides (alanyl-leucine and alanyl-leucyl-alanyl-leucyl) as intermediate steps in the synthesis of covalent primaquine—glycoprotein conjugates that would...

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Autores principales: Trouet, A., Pirson, P., Steiger, R., Masquelier, M., Baurain, R., Gillet, J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1981
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396071/
https://ncbi.nlm.nih.gov/pubmed/6976852
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