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Decrease in susceptibility of Plasmodium falciparum to mefloquine in continuous culture

Chloroquine-resistant P. falciparum, line FCK from Thailand, was tested for susceptibility to mefloquine in continuous culture. The drug resulted in 50% schizont inhibition at the level of 8.0 nmol/ml of culture when tested for the first time. After three months of discontinuous exposure to mefloqui...

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Bibliographic Details
Main Authors: Brockelman, C. R., Monkolkeha, S., Tanariya, P.
Format: Artigo
Language:Inglês
Published: 1981
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396047/
https://ncbi.nlm.nih.gov/pubmed/7018728
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