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C-erbB-2 or mutant Ha-ras induced malignant transformation of immortalized human ovarian surface epithelial cells in vitro

Ovarian cancer is believed to develop from the ovarian surface epithelium through the accumulation of aberrations of oncogenes and/or tumor suppressor genes. However, it is unclear how the gene abnormalities are involved in ovarian carcinogenesis. To elucidate the process, we transfected genes repor...

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Detalhes bibliográficos
Main Authors: Kusakari, T, Kariya, M, Mandai, M, Tsuruta, Y, Hamid, A A, Fukuhara, K, Nanbu, K, Takakura, K, Fujii, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395276/
https://ncbi.nlm.nih.gov/pubmed/14676809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601423
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