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Mutations Affecting the MA Portion of the v-Abl Protein Reveal a Conserved Role of Gag in Abelson Murine Leukemia Virus (MLV) and Moloney MLV

Abelson murine leukemia virus (Ab-MLV) arose from a recombination between gag sequences in Moloney MLV (Mo-MLV) and the c-abl proto-oncogene. The v-Abl oncoprotein encoded by Ab-MLV contains MA, p12, and a portion of CA sequences derived from the gag gene of Mo-MLV. Previous studies indicated that a...

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Bibliographic Details
Main Authors: Yi, Chae-ryun, Rosenberg, Naomi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395225/
https://ncbi.nlm.nih.gov/pubmed/18367522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00089-08
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