Down-regulation of the expression of endothelial NO synthase is likely to contribute to glucocorticoid-mediated hypertension

Hypertension is a side effect of systemically administered glucocorticoids, but the underlying molecular mechanism remains poorly understood. Ingestion of dexamethasone by rats telemetrically instrumented increased blood pressure progressively over 7 days. Plasma concentrations of Na(+) and K(+) and...

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Autors principals: Wallerath, Thomas, Witte, Klaus, Schäfer, Stephan C., Schwarz, Petra M., Prellwitz, Winfried, Wohlfart, Paulus, Kleinert, Hartmut, Lehr, Hans-Anton, Lemmer, Björn, Förstermann, Ulrich
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC23952/
https://ncbi.nlm.nih.gov/pubmed/10557325
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