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A Fusion Inhibitor Prevents Spread of Immunodeficiency Viruses, but Not Activation of Virus-Specific T Cells, by Dendritic Cells

Dendritic cells (DCs) play a key role in innate immune responses, and their interactions with T cells are critical for the induction of adaptive immunity. However, immunodeficiency viruses are efficiently captured by DCs and can be transmitted to and amplified in CD4(+) T cells, with potentially del...

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Detalhes bibliográficos
Main Authors: Frank, I., Stössel, H., Gettie, A., Turville, S. G., Bess, J. W., Lifson, J. D., Sivin, I., Romani, N., Robbiani, M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395170/
https://ncbi.nlm.nih.gov/pubmed/18367527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01987-07
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