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Specific Partial Reduction of Geranylgeranyl Diphosphate by an Enzyme from the Thermoacidophilic Archaeon Sulfolobus acidocaldarius Yields a Reactive Prenyl Donor, Not a Dead-End Product

Geranylgeranyl reductase from Sulfolobus acidocaldarius was shown to catalyze the reduction of geranylgeranyl groups in the precursors of archaeal membrane lipids, generally reducing all four double bonds. However, when geranylgeranyl diphosphate was subjected to the reductase reaction, only three o...

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Detalhes bibliográficos
Main Authors: Sato, Sho, Murakami, Motomichi, Yoshimura, Tohru, Hemmi, Hisashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395040/
https://ncbi.nlm.nih.gov/pubmed/18375567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00082-08
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