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Dihydrolipoamide Dehydrogenase Mutation Alters the NADH Sensitivity of Pyruvate Dehydrogenase Complex of Escherichia coli K-12

Under anaerobic growth conditions, an active pyruvate dehydrogenase (PDH) is expected to create a redox imbalance in wild-type Escherichia coli due to increased production of NADH (>2 NADH molecules/glucose molecule) that could lead to growth inhibition. However, the additional NADH produced by P...

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Main Authors: Kim, Youngnyun, Ingram, L. O., Shanmugam, K. T.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395023/
https://ncbi.nlm.nih.gov/pubmed/18375566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00104-08
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