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Biochemical and Molecular Characterization of a Novel Type of Mutanase from Paenibacillus sp. Strain RM1: Identification of Its Mutan-Binding Domain, Essential for Degradation of Streptococcus mutans Biofilms

A novel type of mutanase (termed mutanase RM1) was isolated from Paenibacillus sp. strain RM1. The purified enzyme specifically hydrolyzed α-1,3-glucan (mutan) and effectively degraded biofilms formed by Streptococcus mutans, a major etiologic agent in the progression of dental caries, even followin...

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Autors principals: Shimotsuura, Isao, Kigawa, Hiromitsu, Ohdera, Motoyasu, Kuramitsu, Howard K., Nakashima, Syozi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394904/
https://ncbi.nlm.nih.gov/pubmed/18326674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02332-07
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