Targeted Inactivation of Francisella tularensis Genes by Group II Introns

Studies of the molecular mechanisms of pathogenesis of Francisella tularensis, the causative agent of tularemia, have been hampered by a lack of genetic techniques for rapid targeted gene disruption in the most virulent subspecies. Here we describe efficient targeted gene disruption in F. tularensis...

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Bibliografiske detaljer
Main Authors: Rodriguez, Stephen A., Yu, Jieh-Juen, Davis, Greg, Arulanandam, Bernard P., Klose, Karl E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2008
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Methods
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394887/
https://ncbi.nlm.nih.gov/pubmed/18310413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02905-07
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