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The JCSG MR pipeline: optimized alignments, multiple models and parallel searches

The success rate of molecular replacement (MR) falls considerably when search models share less than 35% sequence identity with their templates, but can be improved significantly by using fold-recognition methods combined with exhaustive MR searches. Models based on alignments calculated with fold-r...

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Detalhes bibliográficos
Main Authors: Schwarzenbacher, Robert, Godzik, Adam, Jaroszewski, Lukasz
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394805/
https://ncbi.nlm.nih.gov/pubmed/18094477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444907050111
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