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Genome position and gene amplification
BACKGROUND: Amplifications, regions of focal high-level copy number change, lead to overexpression of oncogenes or drug resistance genes in tumors. Their presence is often associated with poor prognosis; however, the use of amplification as a mechanism for overexpression of a particular gene in tumo...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2007
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394771/ https://ncbi.nlm.nih.gov/pubmed/17584934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-6-r120 |
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