Genome position and gene amplification

BACKGROUND: Amplifications, regions of focal high-level copy number change, lead to overexpression of oncogenes or drug resistance genes in tumors. Their presence is often associated with poor prognosis; however, the use of amplification as a mechanism for overexpression of a particular gene in tumo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Gajduskova, Pavla, Snijders, Antoine M, Kwek, Serena, Roydasgupta, Ritu, Fridlyand, Jane, Tokuyasu, Taku, Pinkel, Daniel, Albertson, Donna G
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394771/
https://ncbi.nlm.nih.gov/pubmed/17584934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-6-r120
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge