Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains

BACKGROUND: Francisella tularensis subspecies tularensis and holarctica are pathogenic to humans, whereas the two other subspecies, novicida and mediasiatica, rarely cause disease. To uncover the factors that allow subspecies tularensis and holarctica to be pathogenic to humans, we compared their ge...

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Autors principals: Rohmer, Laurence, Fong, Christine, Abmayr, Simone, Wasnick, Michael, Larson Freeman, Theodore J, Radey, Matthew, Guina, Tina, Svensson, Kerstin, Hayden, Hillary S, Jacobs, Michael, Gallagher, Larry A, Manoil, Colin, Ernst, Robert K, Drees, Becky, Buckley, Danielle, Haugen, Eric, Bovee, Donald, Zhou, Yang, Chang, Jean, Levy, Ruth, Lim, Regina, Gillett, Will, Guenthener, Don, Kang, Allison, Shaffer, Scott A, Taylor, Greg, Chen, Jinzhi, Gallis, Byron, D'Argenio, David A, Forsman, Mats, Olson, Maynard V, Goodlett, David R, Kaul, Rajinder, Miller, Samuel I, Brittnacher, Mitchell J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394750/
https://ncbi.nlm.nih.gov/pubmed/17550600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2007-8-6-r102
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