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Structure of the central RNA recognition motif of human TIA-1 at 1.95 Å resolution

T-cell-restricted intracellular antigen-1 (TIA-1) regulates alternative pre-mRNA splicing in the nucleus, and mRNA translation in the cytoplasm, by recognizing uridine-rich sequences of RNAs. As a step towards understanding of RNA recognition by this regulatory factor, the X-ray structure of the cen...

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Autori principali: Kumar, Amit O., Swenson, Matthew C., Benning, Matthew M., Kielkopf, Clara L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394723/
https://ncbi.nlm.nih.gov/pubmed/18201561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.01.027
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