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Inhibition by secalonic acid D of oxidative phosphorylation and Ca2+-induced swelling in mitochondria isolated from rat livers.

The in vitro biological activity of secalonic acid D, a mycotoxin from Aspergillus ochraceus, was studied to assess its cytotoxicity for isolated rat liver mitochondria. Secalonic acid D uncoupled the oxidative phosphorylation of mitochondria and caused a mild inhibition of state 3 respiration. Seca...

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Bibliografische Detailangaben
Veröffentlicht in:Appl Environ Microbiol
Hauptverfasser: Kawai, K, Nakamaru, T, Maebayashi, Y, Nozawa, Y, Yamazaki, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1983
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239469/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6227285/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.46.4.793-796.1983
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