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Patterns of antigenic diversity and the mechanisms that maintain them

Many of the remaining challenges in infectious disease control involve pathogens that fail to elicit long-lasting immunity in their hosts. Antigenic variation is a common reason for this failure and a contributor to the complexity of vaccine design. Diversifying selection by the host immune system i...

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Detalhes bibliográficos
Main Authors: Lipsitch, Marc, O'Hagan, Justin J
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394542/
https://ncbi.nlm.nih.gov/pubmed/17426010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2007.0229
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