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The Retinoic Acid Receptor-α mediates human T-cell activation and Th2 cytokine and chemokine production
BACKGROUND: We have recently demonstrated that all-trans-retinoic acid (ATRA) and 9-cis-retinoic acid (9-cis RA) promote IL-4, IL-5 and IL-13 synthesis, while decreasing IFN-γ and TNF-α expression by activated human T cells and reduces the synthesis of IL-12p70 from accessory cells. Here, we have de...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394516/ https://ncbi.nlm.nih.gov/pubmed/18416830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-9-16 |
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