Loss of mXinα, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects

The intercalated disk protein Xin was originally discovered in chicken striated muscle and implicated in cardiac morphogenesis. In the mouse, there are two homologous genes, mXinα and mXinβ. The human homolog of mXinα, Cmya1, maps to chromosomal region 3p21.2–21.3, near a dilated cardiomyopathy with...

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Detalhes bibliográficos
Main Authors: Gustafson-Wagner, Elisabeth A., Sinn, Haley W., Chen, Yen-Lin, Wang, Da-Zhi, Reiter, Rebecca S., Lin, Jenny L.-C., Yang, Baoli, Williamson, Roger A., Chen, Ju, Lin, Cheng-I., Lin, Jim J.-C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394510/
https://ncbi.nlm.nih.gov/pubmed/17766470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00806.2007
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