Experimental hemochromatosis due to MHC class I HFE deficiency: Immune status and iron metabolism

The puzzling linkage between genetic hemochromatosis and histocompatibility loci became even more so when the gene involved, HFE, was identified. Indeed, within the well defined, mainly peptide-binding, MHC class I family of molecules, HFE seems to perform an unusual yet essential function. As yet,...

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Main Authors: Bahram, Seiamak, Gilfillan, Susan, Kühn, Lukas C., Moret, Rémy, Schulze, Johannes B., Lebeau, Annette, Schümann, Klaus
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC23944/
https://ncbi.nlm.nih.gov/pubmed/10557317
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