A multicentre phase II trial of bryostatin-1 in patients with advanced renal cancer

Protein kinase C (PKC) has a critical role in several signal transduction pathways, and is involved in renal cancer pathogenesis. Bryostatin-1 modulates PKC activity and has antitumour effects in preclinical studies. We conducted a multicentre phase II clinical trial in patients with advanced renal...

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Detalhes bibliográficos
Main Authors: Madhusudan, S, Protheroe, A, Propper, D, Han, C, Corrie, P, Earl, H, Hancock, B, Vasey, P, Turner, A, Balkwill, F, Hoare, S, Harris, A L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2003
Assuntos:
Clinical
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394342/
https://ncbi.nlm.nih.gov/pubmed/14562010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601321
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