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c-Myc alters the DNA damage-induced G2/M arrest in human mammary epithelial cells

Effects of c-Myc overexpression on the DNA damage-induced G2/M checkpoint were studied in finite lifespan, normal human mammary epithelial cells (HMECs). Previously, we showed that c-Myc attenuates G1/S arrest and leads to an inappropriate entry of cells with damaged DNA into the S phase, following...

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Detalles Bibliográficos
Main Authors: Sheen, J-H, Woo, J-K, Dickson, R B
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394331/
https://ncbi.nlm.nih.gov/pubmed/14562020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601307
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