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Detection of p53 mutations in precancerous gastric tissue

Intestinal-type gastric cancer is preceded by gastritis and intestinal metaplasia. There is uncertainty regarding the stage at which genetic alterations in the p53 gene occur. Reactive oxygen species (ROS) may participate in the production of mutations and the inactivation of p53 is due to infection...

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Autori principali: Morgan, C, Jenkins, G J S, Ashton, T, Griffiths, A P, Baxter, J N, Parry, E M, Parry, J M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394306/
https://ncbi.nlm.nih.gov/pubmed/14520466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601302
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