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PAX7 expression in embryonal rhabdomyosarcoma suggests an origin in muscle satellite cells

Rhabdomyosarcoma (RMS) is a common paediatric soft tissue sarcoma that resembles developing foetal skeletal muscle. Tumours of the alveolar subtype frequently harbour one of two characteristic translocations that juxtapose PAX3 or PAX7, and the forkhead-related gene FKHR (FOXO1A). The embryonal subt...

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Bibliografiske detaljer
Main Authors: Tiffin, N, Williams, R D, Shipley, J, Pritchard-Jones, K
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394255/
https://ncbi.nlm.nih.gov/pubmed/12865925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601040
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