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No major tumorigenic role for β-catenin in serrated as opposed to conventional colorectal adenomas
Intracellular redistribution of β-catenin through mutation of the adenomatous polyposis coli (APC) gene has been proposed as an early tumorigenic event in most colorectal tumours. In serrated adenoma (SA), a newly recognised subtype of colorectal adenoma, APC mutations are uncommon, and the contribu...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394200/ https://ncbi.nlm.nih.gov/pubmed/12838317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601070 |
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