Expression of a Mutant Form of the Ferritin Light Chain Gene Induces Neurodegeneration and Iron Overload in Transgenic Mice

Increased iron levels and iron-mediated oxidative stress play an important role in the pathogenesis of many neurodegenerative diseases. The finding that mutations in the ferritin light polypeptide (FTL) gene cause a neurodegenerative disease known as neuroferritinopathy or hereditary ferritinopathy...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Vidal, Ruben, Miravalle, Leticia, Gao, Xiaoying, Barbeito, Ana G., Baraibar, Martin A., Hekmatyar, Shahryar K., Widel, Mario, Bansal, Navin, Delisle, Marie B., Ghetti, Bernardino
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394191/
https://ncbi.nlm.nih.gov/pubmed/18171923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3962-07.2008
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados